{"id":198,"date":"2017-11-16T12:02:24","date_gmt":"2017-11-16T14:02:24","guid":{"rendered":"http:\/\/inct-bionat.iq.unesp.br\/?page_id=198"},"modified":"2017-11-22T11:52:54","modified_gmt":"2017-11-22T13:52:54","slug":"maria-claudia-marx-young","status":"publish","type":"page","link":"http:\/\/inct-bionat.iq.unesp.br\/en\/participantes\/pesquisadores\/maria-claudia-marx-young\/","title":{"rendered":"Maria Cl\u00e1udia Marx Young"},"content":{"rendered":"

Sorry, this entry is only available in Portugu\u00eas do Brasil<\/a>. For the sake of viewer convenience, the content is shown below in the alternative language. You may click the link to switch the active language.<\/p>

<\/p>\n

\"\"Doutora<\/h2>\n

Laborat\u00f3rio: <\/strong>N\u00facleo de Pesquisa em Fisiologia e Bioqu\u00edmica<\/p>\n

Telefone:<\/strong>\u00a0+55 11 50676170<\/p>\n

E-mail:\u00a0<\/strong>marxyoungmc@gmail.com<\/a><\/p>\n

Lattes:\u00a0<\/strong>http:\/\/lattes.cnpq.br\/3354457350968761<\/a><\/p>\n

Linha de Pesquisa<\/h2>\n

Bioprospec\u00e7\u00e3o de produtos naturais com atividades antif\u00fangica e anticolinester\u00e1sica.<\/p>\n

Descri\u00e7\u00e3o<\/h2>\n

A flora tropical do Brasil pode ser considerada uma das fontes mais ricas e pouco exploradas em substratos usados na busca de novos modelos moleculares que podem, a partir de estudos de bioprospec\u00e7\u00e3o, qu\u00edmicos e farmacol\u00f3gicos, levar \u00e0 descoberta de novos medicamentos para a cura ou controle de diversas doen\u00e7as. Neste contexto, nosso grupo vem se dedicando \u00e0 bioprospec\u00e7\u00e3o e estudo qu\u00edmico de esp\u00e9cies nativas brasileiras detentoras de atividades antif\u00fangicas, anticolinester\u00e1sica e antioxidante aplicados \u00e0 sele\u00e7\u00e3o de esp\u00e9cies com potencial terap\u00eautico e \u00e0 pol\u00edtica de conserva\u00e7\u00e3o e utiliza\u00e7\u00e3o sustent\u00e1vel da biodiversidade vegetal<\/p>\n

Principais Trabalhos Desenvolvidos<\/h2>\n
    \n
  1. Murakami, Cynthia; Cordeiro, In\u00eas; Scotti, Marcos Tullius , Moreno, Paulo Roberto H.. Young<\/strong>, Maria Cl\u00e1udia M<\/strong>. Chemical Composition, Antifungal and Antioxidant Activities of Hedyosmum brasiliense<\/em> Mart. ex Miq. (Chloranthaceae) Essential Oils. Medicines, v. 4, p. 55-67, 2017<\/strong> doi:10.3390\/medicines4030055<\/li>\n
  2. Cabral, Rodrigo Sant’Ana; Allard, Pierre-Marie; Marcourt, Laurence;\u00a0Young, Maria Cl\u00e1udia Marx<\/strong>\u00a0; Queiroz, Emerson Ferreira; Wolfender, Jean-Luc. Targeted Isolation of Indolopyridoquinazoline Alkaloids from Conchocarpus fontanusianus<\/em> Based on Molecular Networks. Journal of Natural Products (Print), v. 79, p. 2270- 2278, 2016.<\/li>\n
  3. Fardin, K\u00e1ssia Mantovan ;\u00a0Young, Maria Cl\u00e1udia Marx<\/strong>\u00a0. Antifungal potential of Avicennia schaueriana<\/em> Stapf & Leech. (Acanthaceae) against Cladosporium<\/em> and Colletotrichum <\/em>species. Letters in Applied Microbiolog, v. 61, p. 50-57, 2015.<\/li>\n
  4. Machado, L. P.; Carvalho, L. R. ;\u00a0Young, Maria Claudia M.<\/strong>\u00a0;\u00a0Cardoso-Lopes, E. M.\u00a0;\u00a0Centeno, D. C.\u00a0; Zamboti-Vilella, L. ; Colepicolo, P. ; Yokoya, Nair Sumie . Evaluation of acetylcholinesterase inhibitory activity of Brazilian red macroalgae organic extracts. Revista Brasileira de Farmacognosia (Impresso), v. 25, p. 657-662, 2015.<\/li>\n
  5. \u00a0Ferreira, Edgard A. ;\u00a0Reigada, Juliana B.\u00a0;\u00a0Correia, Mauro V.\u00a0;\u00a0Young, Maria C. M.<\/strong>\u00a0;\u00a0Guimar\u00e3es, Elsie F.\u00a0; Franchi, Gilberto C. ; Nowill, Alexandre E. ; Lago, Jo\u00e3o H. G. ; Yamaguchi, Lydia F. ;\u00a0Kato, Massuo J.\u00a0. Antifungal and Cytotoxic 2-Acylcyclohexane-1,3-diones from Peperomia alata<\/em>\u00a0and\u00a0P. trineura<\/em>. Journal of Natural Products (Print), v. 77, p. 1377-1382, 2014.<\/li>\n
  6. Machado, Levi Pop\u00e9rmaye; De Carvalho, Luciana Retz;\u00a0Young, Maria Cl\u00e1udia Marx<\/strong>\u00a0;\u00a0Zambotti-VillelaIla, Leonardo\u00a0;\u00a0Colepicolo, Pio\u00a0; Anreguetti, Daniel Xavier ;\u00a0Yokoya, Nair S.\u00a0. Comparative chemical analysis and antifungal activity of Ochtodes secundiramea<\/em> (Rhodophyta) extracts obtained using different biomass processing methods. Journal of Applied Phycology, v. 26, p. 2029-2035, 2014.<\/li>\n
  7. Chapla, Vanessa\u00a0;\u00a0Zeraik, Maria\u00a0; Leptokarydis, Ioanis ; Silva, Geraldo ; Bolzani, Vanderlan ;\u00a0Young, Maria<\/strong>\u00a0;\u00a0Pfenning, Ludwig\u00a0; Ara\u00fajo, Angela . Antifungal Compounds Produced by Colletotrichum gloeosporioides<\/em>, an Endophytic Fungus from Michelia champaca<\/em>. Molecules (Basel. Online), v. 19, p. 19243-19252, 2014.<\/li>\n
  8. Murakami, C.\u00a0;\u00a0Lago, J. H. G.\u00a0; Perazzo, F. P. ;\u00a0Ferreira, K. S.\u00a0;\u00a0Lima, M. E. L.\u00a0;\u00a0Moreno, P. R. H.\u00a0;\u00a0Young, M. C. M.<\/strong>\u00a0. Chemical Composition and Antimicrobial Activity of Essential Oils from Chromolaena laevigata<\/em> during Flowering and Fruiting Stages. Chemistry & Biodiversity (Print), v. 10, p. 621-627, 2013.<\/li>\n
  9. Cabral, R. S.\u00a0; Sartori, M. C. ;\u00a0Cordeiro, I\u00a0;\u00a0Queiroga, C. L.\u00a0;\u00a0Eberlin, M. N.\u00a0;\u00a0Lago J. H. G.\u00a0;\u00a0Moreno, P. R. H.\u00a0;\u00a0Young, M. C. M.<\/strong>\u00a0. Anticholinesterase activity evaluation of alkaloids and coumarin from stems of Conchocarpus fontanesianus<\/em> (A. St.-Hil.) Kallunki & Pirani (Rutaceae). Revista Brasileira de Farmacognosia (Impresso), v. 22, p. 374-380, 2012.<\/li>\n
  10. Francisco, Welington ;\u00a0Pivatto, Marcos\u00a0;\u00a0Danuello, Amanda\u00a0;\u00a0Regasini, Luis O.\u00a0;\u00a0Baccini, Luciene R.\u00a0;\u00a0Young, Maria C. M.<\/strong>\u00a0;\u00a0Lopes, Norberto P.\u00a0;\u00a0Lopes, Jo\u00e3o L. C.\u00a0;\u00a0Bolzani, Vanderlan S.\u00a0. Pyridine Alkaloids from As Acetylcholinesterase Inhibitors. Journal of Natural Products (Print), v. 75, p. 408-413, 2012.<\/li>\n<\/ol>\n

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