{"id":455,"date":"2018-05-14T19:45:59","date_gmt":"2018-05-14T22:45:59","guid":{"rendered":"http:\/\/inct-bionat.iq.unesp.br\/?page_id=455"},"modified":"2018-05-14T19:45:59","modified_gmt":"2018-05-14T22:45:59","slug":"jose-delano-barreto-marinho-filho","status":"publish","type":"page","link":"http:\/\/inct-bionat.iq.unesp.br\/en\/participantes\/pesquisadores\/jose-delano-barreto-marinho-filho\/","title":{"rendered":"Jos\u00e9 Delano Barreto Marinho Filho"},"content":{"rendered":"

Sorry, this entry is only available in Portugu\u00eas do Brasil<\/a>. For the sake of viewer convenience, the content is shown below in the alternative language. You may click the link to switch the active language.<\/p>

<\/p>\n

\"\"Prof. Doutor Adjunto A<\/strong><\/h2>\n

Laborat\u00f3rio: <\/strong>N\u00facleo de Pesquisa em Biodiversidade e Biotecnologia (Biotec)\/Laborat\u00f3rio de Cultura de C\u00e9lulas do Delta (LCCdelta)<\/p>\n

Telefone:<\/strong>\u00a0+55 86 99999-7975<\/p>\n

E-mail:\u00a0<\/strong>delanomarinho@gmail.com<\/a><\/p>\n

Lattes:\u00a0<\/strong>http:\/\/buscatextual.cnpq.br\/buscatextual\/visualizacv.do?id=K4712534T8<\/a><\/p>\n

Linha de Pesquisa<\/h2>\n

Desenvolvimento, valida\u00e7\u00e3o e aplica\u00e7\u00e3o de novas biomol\u00e9culas e sistemas de veicula\u00e7\u00e3o com potencial diagn\u00f3stico e terap\u00eautico<\/p>\n

Descri\u00e7\u00e3o<\/h2>\n

Isolamento e caracteriza\u00e7\u00e3o de extratos e mol\u00e9culas naturais para determinar atividade biol\u00f3gica (antibacteriano e antitumoral), em adi\u00e7\u00e3o \u00e9 realizado formula\u00e7\u00f5es nanoestruturadas (met\u00e1licas) com o objetivo de facilitar a entrega ao alvo molecular dessas mol\u00e9culas obtidas ou de mol\u00e9culas j\u00e1 conhecidas.<\/p>\n

Principais Trabalhos Desenvolvidos<\/h2>\n
    \n
  1. In vitro antitumor effect of a lignan isolated from Combretum fruticosum, trachelogenin, in HCT-116 human colon cancer cells. TOXICOLOGY IN VITRO<\/strong> , v. 47, p. 129-136, 2018.<\/li>\n
  2. Cytotoxicity against tumor cell lines and anti-inflammatory properties of chitinases from Calotropis procera latex. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY<\/strong>, v. 1, p. 1-9, 2017.<\/li>\n
  3. New insights into 3-(aminomethyl)naphthoquinones: Evaluation of cytotoxicity, electrochemical behavior and search for structure-activity correlation. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (PRINT)<\/strong>, v. 26, p. 3537-3542, 2016.<\/li>\n
  4. Growth inhibitory effects of 3 -nitro-3-phenylamino nor-beta-lapachone against HL-60: A redox-dependent mechanism. TOXICOLOGY IN VITRO<\/strong>, v. 1, p. 1-10, 2012.<\/li>\n
  5. Oxidative stress induction by (+)-cordiaquinone J triggers both mitochondria-dependent apoptosis and necrosis in leukemia cells. CHEMICO-BIOLOGICAL INTERACTIONS (PRINT)<\/strong>, v. 183, p. 369-379, 2010.<\/li>\n
  6. Novel platinum(ii) complexes of 3-(aminomethyl)naphthoquinone Mannich bases: synthesis, crystal structure and cytotoxic activities. DALTON TRANSACTIONS (2003. Print)<\/strong>, p. 1-14, 2010.<\/li>\n<\/ol>\n

    <\/p>","protected":false},"excerpt":{"rendered":"

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