{"id":631,"date":"2018-10-07T12:41:11","date_gmt":"2018-10-07T15:41:11","guid":{"rendered":"http:\/\/inct-bionat.iq.unesp.br\/?page_id=631"},"modified":"2018-10-07T12:48:18","modified_gmt":"2018-10-07T15:48:18","slug":"amanda-danuello-pivatto-2","status":"publish","type":"page","link":"http:\/\/inct-bionat.iq.unesp.br\/en\/participantes\/pesquisadores\/amanda-danuello-pivatto-2\/","title":{"rendered":"(Portugu\u00eas do Brasil) Amanda Danuello Pivatto"},"content":{"rendered":"

Sorry, this entry is only available in Portugu\u00eas do Brasil<\/a>. For the sake of viewer convenience, the content is shown below in the alternative language. You may click the link to switch the active language.<\/p>

<\/p>\n

\"\"Doutora<\/h2>\n

Laborat\u00f3rio: <\/strong>N\u00facleo de Desenvolvimento de Compostos Bioativos (NDCBio)<\/p>\n

Telefone:<\/strong>\u00a0+55 34 98800-7755<\/p>\n

E-mail:\u00a0<\/strong>amandanuello@gmail.com<\/a> ou amanda.danuello@uftm.edu.br<\/a><\/p>\n

Lattes:\u00a0<\/strong>http:\/\/lattes.cnpq.br\/0700488873965276<\/a><\/p>\n

Linha de Pesquisa<\/h2>\n

Qu\u00edmica Medicinal e Qu\u00edmica de Produtos Naturais, atuando principalmente nos seguintes temas: planejamento e s\u00edntese de subst\u00e2ncias biotivas; modifica\u00e7\u00e3o estrutural de produtos naturais bioativos e s\u00edntese org\u00e2nica seguindo as diretrizes da Qu\u00edmica Verde.<\/p>\n

Descri\u00e7\u00e3o<\/h2>\n

A professora Amanda Danuello Pivatto \u00e9 coordenadora do N\u00facleo de Desenvolvimento de Compostos Bioativos, que visa a obten\u00e7\u00e3o de compostos de interesse farmacol\u00f3gico, principalmente para doen\u00e7as negligenciadas, c\u00e2ncer e doen\u00e7as do sistema nervoso central. Atualmente \u00e9 professora (adjunto II) na Universidade Federal do Tri\u00e2ngulo Mineiro (UFTM) em Uberaba\/MG e subcoordenadora geral do Programa de P\u00f3s-Gradua\u00e7\u00e3o Multic\u00eantrico em Qu\u00edmica de Minas Gerias (PPGMQ-MG), onde atua como orientadora de mestrado e doutorado.<\/p>\n

Principais Trabalhos Desenvolvidos<\/h2>\n
    \n
  1. GON\u00c7ALVES, A.C.R.; CARNEIRO, Z. A.; OLIVEIRA, C. G.; DANUELLO, A.; GUERRA, W.; OLIVEIRA, R. J.; FERREIRA, F. B.; VELOSO-SILVA, L. L.W.; BATISTA, F. A. H.; BORGES, J. C.; DE ALBUQUERQUE, S.; DEFLON, V. M.; MAIA, P. I. S. Pt II , Pd II and Au III complexes with a thiosemicarbazone derived from diacethylmonooxime: Structural analysis, trypanocidal activity, cytotoxicity and first insight into the antiparasitic mechanism of action. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v. 141, p. 615-631, 2017.<\/li>\n
  2. VALLI, M.; BETTI, A. H.; DANUELLO, A.; PIVATTO, M.; CENTURIAO, F.; ANTONIO, C. B.; RATES, S. M. K.; BOLZANI, V. S. Pyridinic analog of the natural product (\u2212)-spectaline as potential adjuvant for the treatment of central nervous system disorders. Bioorganic & Medicinal Chemistry Letters, v. 25, p. 2247-2250, 2015.<\/li>\n
  3. PIVATTO, M.; BACCINI, L. R.; SHARMA, A.; NAKABASHI, M.; DANUELLO, A.; VIEGAS JUNIOR, C.; GARCIA, C. R. S.; BOLZANI, V. S. Antimalarial activity of piperidine Alkaloids from Senna spectabilis<\/em> and semisynthetic derivatives. Journal of the Brazilian Chemical Society, v. 25, p. 1900-1906, 2014.<\/li>\n
  4. DANUELLO, A.; ROMEIRO, N. C.; GIESEL, G. M.; PIVATTO, M.; VIEGAS J\u00daNIOR, C.; VERLI, H.; BARREIRO, E. J.; FRAGA, C. A. M.; CASTRO, N. G.; BOLZANI, V. S. Molecular docking and molecular dynamic studies of semi-synthetic piperidine alkaloids as acetylcholinesterase inhibitors. Journal of the Brazilian Chemical Society, v. 23, p. 163-170, 2012.<\/li>\n
  5. VIEGAS J\u00daNIOR, C.; DANUELLO, A.; BOLZANI, V. S.; BARREIRO, E. J.; FRAGA, C.A. M. Molecular Hybridization: A Useful Tool in the Design of New Drug Prototypes. Current Medicinal Chemistry (Hilversum), v. 14, p. 1829-1852, 2007.<\/li>\n<\/ol>\n

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